Questions on neoplasia

 

Epidemiology

Q: I read that some cancers are more common in men than in women (e.g. lung, liver and bladder cancer) and vice versa (meningioma, thyroid cancer). Why is this? Could it be caused by hormones or some other factors or is it just a complete mystery?

Q: What is the explanation why some benign tumors turn into malignant ones whereas others do not?

Nomenclature

Q: Why is it called an angiosarcoma and not an angiocarcinoma?

Q: What is the difference between leukemia and lymphoma?

Q: Is the neoplastic tissue named after its originating cell type or the cell type it appears like?

Q: Dysplasia vs. dysplastic

Q: How come it is called a hepatocellular carcinoma and not a sarcoma?

Q: What is the difference between metastasis and metaplasia?

Q: What is the difference between architectural atypia and cytological atypia?

Q: Phenotypic mutator

Morphology

Q: Giant cells in osteosarcomas

Q: Morphology of a leiomyoma

Q: Tumor stromal cells

Metastasis

Q: 1) Do all malignant tumors metastasize?
2) A teacher told me that brain tumors never metastasize outside the brain – why is this?

Q: Does anyone know of any relationship between the spread of tumors and lymph vessel representation in the given organ.

Q: Metastasis of lung cancer

Q: How do metastasized tumor cells adapt to the new environment?

Q: Why does the lung and breast tissue have a high tendency for early blood metastasis?

Criteria of malignancy

Q: What are the criteria of malignancy?

Q: Why can one not use desmoplasia as a histologic criterium of malignancy???

Q: What is the difference between anaplasia and dysplasia?

Q: What is the difference between metaplasia, dysplasia and anaplasia?  Is dysplasia a reversible process and as such a cellular adaptation?

Q: Is dysplasia reversible?

Q: What is the difference between neoplasia , dysplasia and anaplasia?

Q: Can someone describe to me exactely what desmoplasia means?

Q: Lymphoma – both malignant and benign?

Hallmarks of cancer

Q: Question on the transition between benign and malignant tumors in relation to mutations.

 Q: What are the differences between pre-malignancy and benignancy?

Q: 1) Do all cancers stem from tissue which has undergone benign ‘transformation’ or may cancer evolve in completely normal tissue from ‘one day to another’? 2) Which tumors most often progress from benignity to malignancy?

Q: Tumor supressor genes