2 thoughts on “Q: Does liquefactive necrosis occur outside the CNS?”
Yes, it may occur in focal bacterial or fungal infections of the skin: The microbes cause inflammation and leukocytes subsequently release enzymes which digest (liquefy) the tissue
(also mentioned by Flemming in the necrosis lecture).
Cell death occurs first – either through cellular swelling (Oncosis) or cellular shrinkage (Apoptosis) or Aponecrosis (Apoptosis+Necrosis). Then the dead cell undergoes Necrosis. Only dead cells undergo Necrosis, and the term is specific & limited only for dead cells. Necrosis is not how cells die; it’s what happens to them after death.
Nuclear changes – Pyknosis is common to all cell death processes. It’s the next step that differs. Oncosis will show karyolysis. Apoptosis will show karyorhexis
Yes, it may occur in focal bacterial or fungal infections of the skin: The microbes cause inflammation and leukocytes subsequently release enzymes which digest (liquefy) the tissue
(also mentioned by Flemming in the necrosis lecture).
Cell death occurs first – either through cellular swelling (Oncosis) or cellular shrinkage (Apoptosis) or Aponecrosis (Apoptosis+Necrosis). Then the dead cell undergoes Necrosis. Only dead cells undergo Necrosis, and the term is specific & limited only for dead cells. Necrosis is not how cells die; it’s what happens to them after death.
Nuclear changes – Pyknosis is common to all cell death processes. It’s the next step that differs. Oncosis will show karyolysis. Apoptosis will show karyorhexis